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Genetically modified CD4 T cells

Showing 1 - 25 of >10,000
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Hiv Trial in Philadelphia (CD4 CAR+CCR5 ZFN T-cells)

Active, not recruiting
  • Hiv
  • CD4 CAR+CCR5 ZFN T-cells
  • Philadelphia, Pennsylvania
    University of Pennsylvania
Jan 6, 2022

DLBCL, Grade 3b Follicular Lymphoma, Primary Mediastinal (Thymic) Large B-Cell Lymphoma Trial (biological, procedure, drug,

Not yet recruiting
  • Diffuse Large B-Cell Lymphoma
  • +6 more
  • Axicabtagene Ciloleucel
  • +10 more
  • (no location specified)
Jan 13, 2023

Hiv Trial in Philadelphia (Autologous CD4 T-Cells)

Completed
Has Results
  • Hiv
  • Autologous CD4 T-Cells
  • Philadelphia, Pennsylvania
    University of Pennsylvania
Nov 13, 2022

Leukemia, Acute Lymphoblastic Leukemia Trial in New York (gene-modified T cells targeted)

Active, not recruiting
  • Leukemia
  • Acute Lymphoblastic Leukemia
  • gene-modified T cells targeted
  • New York, New York
    Memorial Sloan Kettering Cancer Center
Feb 1, 2023

Ovarian Cancer Trial (Autologous genetically modified ADP-A2M4CD8 cells, Autologous genetically modified ADP-A2M4CD8 cells in

Not yet recruiting
  • Ovarian Cancer
  • Autologous genetically modified ADP-A2M4CD8 cells
  • Autologous genetically modified ADP-A2M4CD8 cells in combination with Nivolumab
  • (no location specified)
Jan 31, 2023

Acute Myeloid Leukemia, in Relapse, Acute Myeloid Leukemia Refractory Trial in Germany (Cyclophosphamide (Non-IMP,

Not yet recruiting
  • Acute Myeloid Leukemia, in Relapse
  • Acute Myeloid Leukemia Refractory
  • Cyclophosphamide (Non-IMP, Lymphodepletion)
  • +3 more
  • Ulm, Baden-Württemberg, Germany
  • +4 more
Jul 24, 2023

Acute Lymphocytic Leukemia, Lymphoma Trial in New York (Biological/Genetically Modified T cells, Cyclophosphamide-based chemo)

Active, not recruiting
  • Acute Lymphocytic Leukemia
  • Lymphoma
  • Biological/Genetically Modified T cells
  • Cyclophosphamide-based chemotherapy
  • New York, New York
    Memorial Sloan Kettering Cancer Center
Jan 3, 2023

B-Cell Non-Hodgkin Lymphoma, DLBCL, Mantle Cell Lymphoma Trial in Duarte (Anti-CD19-CAR CMV-specific T-lymphocytes, Autologous

Not yet recruiting
  • B-Cell Non-Hodgkin Lymphoma
  • +7 more
  • Anti-CD19-CAR CMV-specific T-lymphocytes
  • +3 more
  • Duarte, California
    City of Hope Medical Center
Jun 28, 2022

Solid Tumors Trial in New York (procedure, drug, device, genetic)

Active, not recruiting
  • Solid Tumors
  • Production of Genetically-modified T cells
  • +4 more
  • New York, New York
    Memorial Sloan Kettering Cancer Center
Sep 1, 2022

High Grade B-Cell Non-Hodgkin's Lymphoma, Intermediate Grade B-Cell Non-Hodgkin's Lymphoma, Recurrent B-Cell Non-Hodgkin

Not yet recruiting
  • High Grade B-Cell Non-Hodgkin's Lymphoma
  • +3 more
  • Anti-CD19-CAR CMV-specific T-lymphocytes
  • +9 more
  • Duarte, California
    City of Hope Medical Center
Apr 5, 2023

Anaplastic Large Cell Lymphoma, Peripheral T Cell Lymphoma, Extranodal NK/T-cell Lymphoma Trial in Duarte, Nashville, Houston

Active, not recruiting
  • Anaplastic Large Cell Lymphoma
  • +4 more
  • Duarte, California
  • +3 more
Jul 21, 2022

ß-thalassemia Trial (BD211)

Not yet recruiting
  • β-thalassemia
  • BD211
  • (no location specified)
Mar 15, 2023

ß-thalassemia Trial in Shanghai (BD211)

Not yet recruiting
  • β-thalassemia
  • BD211
  • Shanghai, China
    Shanghai Ruijin Hospital
Mar 16, 2023

Leukemia, Lymphoma Trial in United States (SCRI-CAR22v2)

Recruiting
  • Leukemia
  • Lymphoma
  • SCRI-CAR22v2
  • Los Angeles, California
  • +4 more
Jan 18, 2023

Adult Grade III Lymphomatoid Granulomatosis, Cutaneous B-cell Non-Hodgkin Lymphoma, MALT Trial in Duarte (biological, procedure,

Active, not recruiting
  • Adult Grade III Lymphomatoid Granulomatosis
  • +23 more
  • autologous CD19CAR-CD28-CD3zeta-EGFRt-expressing Tcm-enriched T cells
  • +2 more
  • Duarte, California
    City of Hope Medical Center
Jan 4, 2023

Advanced Pleural Malignant Mesothelioma, HLA-A*0201 Positive Cells Present, Recurrent Non-Small Cell Lung Carcinoma Trial in

Terminated
Has Results
  • Advanced Pleural Malignant Mesothelioma
  • +10 more
  • Aldesleukin
  • +4 more
  • Seattle, Washington
    Fred Hutch/University of Washington Cancer Consortium
Aug 16, 2021

HIV-1 Infections Trial in Washington (HAART, T cells)

Completed
  • HIV-1 Infections
  • Washington, District of Columbia
    Walter Reed Army Medical Center
Aug 17, 2022

Relapsed B-Cell Acute Lymphoblastic Leukemia Trial in Boston, New York (procedure, drug, biological)

Active, not recruiting
  • Relapsed B-Cell Acute Lymphoblastic Leukemia
  • leukapheresis or collection of PBMCs
  • +2 more
  • Boston, Massachusetts
  • +1 more
Jan 26, 2022

Chronic Lymphocytic Leukemia (CLL), Relapsed, Refractory Trial in New York (EGFRt/19-28z/4-1BBL CAR T cells)

Active, not recruiting
  • Chronic Lymphocytic Leukemia (CLL)
  • +2 more
  • EGFRt/19-28z/4-1BBL CAR T cells
  • New York, New York
    Memorial Sloan Kettering Cancer Center
Apr 1, 2022

Diffuse Midline Glioma, H3 K27M-Mutant Trial in San Francisco (Cyclophosphamide, Fludarabine, Autologous Anti-H3.3K27M

Not yet recruiting
  • Diffuse Midline Glioma, H3 K27M-Mutant
  • San Francisco, California
    University of California, San Francisco
Aug 15, 2022

B Cell Leukemia Trial in Seattle (Autologous CD19 CAR+ EGFTt + T cells)

Active, not recruiting
  • B Cell Leukemia
  • Autologous CD19 CAR+ EGFTt + T cells
  • Seattle, Washington
    Seattle Children's Hospital
Feb 15, 2022

Glioblastoma Trial in Birmingham (Autologous genetically modified gamma-delta T cells, Allogeneic genetically modified

Not yet recruiting
  • Glioblastoma
  • Autologous genetically modified gamma-delta T cells
  • Allogeneic genetically modified gamma-delta T cells
  • Birmingham, Alabama
    University of Alabama at Birmingham
Dec 16, 2022

HIV Trial in Cincinnati (SB-728-T, Expanded unmodified autologous CD4+ T cells)

Active, not recruiting
  • HIV Infections
  • SB-728-T
  • Expanded unmodified autologous CD4+ T cells
  • Cincinnati, Ohio
    University of Cincinnati
Jan 1, 2022

T-cell Acute Lymphoblastic Leukemia, T-cell Acute Lymphoblastic Lymphoma, Acute Myeloid Leukemia Trial in Beijing, Shenzhen,

Recruiting
  • T-cell Acute Lymphoblastic Leukemia
  • +3 more
  • Universal CD7-specific CAR gene-engineered T cells
  • Beijing, Beijing, China
  • +2 more
Aug 17, 2023

Pancreatic Ductal Adenocarcinoma, NSCLC, Colorectal Cancer Trial (AFNT-211)

Not yet recruiting
  • Pancreatic Ductal Adenocarcinoma
  • +4 more
  • (no location specified)
Oct 23, 2023